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The Tumor Microenvironment and Strategies to Improve Drug Distribution

The microenvironment within tumors is composed of a heterogeneous mixture of cells with varying levels of nutrients and oxygen. Differences in oxygen content result in survival or compensatory mechanisms within tumors that may favor a more malignant or lethal phenotype. Cells that are rapidly prolif...

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Detalhes bibliográficos
Main Authors: Saggar, Jasdeep K., Yu, Man, Tan, Qian, Tannock, Ian F.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677151/
https://ncbi.nlm.nih.gov/pubmed/23772420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2013.00154
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