Determination of DNA sequence changes induced by ethyl methanesulfonate in human cells, using a shuttle vector system.

The DNA sequence changes for 54 mutations induced in human cells by the alkylating agent ethyl methanesulfonate are reported. The mutations were obtained by using a shuttle vector system with the bacterial lacI gene as the target. Of the 54 mutations obtained, 53 were G:C to A:T transitions.

Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Lebkowski, J S, Miller, J H, Calos, M P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1986
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC367715/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3023907/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.6.5.1838-1842.1986
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