Determination of DNA sequence changes induced by ethyl methanesulfonate in human cells, using a shuttle vector system.
The DNA sequence changes for 54 mutations induced in human cells by the alkylating agent ethyl methanesulfonate are reported. The mutations were obtained by using a shuttle vector system with the bacterial lacI gene as the target. Of the 54 mutations obtained, 53 were G:C to A:T transitions.
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| Publicat a: | Mol Cell Biol |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
1986
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC367715/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3023907/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.6.5.1838-1842.1986 |
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