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Targeting Microglia-Mediated Neurotoxicity: The Potential of NOX2 Inhibitors

Microglia are key sentinels of central nervous system health and their dysfunction has been widely implicated in the progressive nature of neurodegenerative diseases. While microglia can produce a host of factors that are toxic to neighboring neurons, NOX2 has been implicated as a common and essenti...

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Detalhes bibliográficos
Main Authors: Surace, Michael J., Block, Michelle L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677079/
https://ncbi.nlm.nih.gov/pubmed/22581365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-012-1015-4
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