Posttranslational Modifications of GLUT4 Affect Its Subcellular Localization and Translocation

The facilitative glucose transporter type 4 (GLUT4) is expressed in adipose and muscle and plays a vital role in whole body glucose homeostasis. In the absence of insulin, only ~1% of cellular GLUT4 is present at the plasma membrane, with the vast majority localizing to intracellular organelles. GLU...

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Bibliographic Details
Main Authors: Sadler, Jessica B. A., Bryant, Nia J., Gould, Gwyn W., Welburn, Cassie R.
Format: Artigo
Language:Inglês
Published: Molecular Diversity Preservation International (MDPI) 2013
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676823/
https://ncbi.nlm.nih.gov/pubmed/23665900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms14059963
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