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Sorting of GLUT4 into its insulin-sensitive store requires the Sec1/Munc18 protein mVps45

Insulin stimulates glucose transport in fat and muscle cells by regulating delivery of the facilitative glucose transporter, glucose transporter isoform 4 (GLUT4), to the plasma membrane. In the absence of insulin, GLUT4 is sequestered away from the general recycling endosomal pathway into specializ...

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Bibliografski detalji
Glavni autori: Roccisana, Jennifer, Sadler, Jessica B. A., Bryant, Nia J., Gould, Gwyn W.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727931/
https://ncbi.nlm.nih.gov/pubmed/23741049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-01-0011
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