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The deubiquitinating enzyme USP25 binds tankyrase and regulates trafficking of the facilitative glucose transporter GLUT4 in adipocytes

Key to whole body glucose homeostasis is the ability of fat and muscle cells to sequester the facilitative glucose transporter GLUT4 in an intracellular compartment from where it can be mobilized in response to insulin. We have previously demonstrated that this process requires ubiquitination of GLU...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sadler, Jessica B. A., Lamb, Christopher A., Welburn, Cassie R., Adamson, Iain S., Kioumourtzoglou, Dimitrios, Chi, Nai-Wen, Gould, Gwyn W., Bryant, Nia J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423145/
https://ncbi.nlm.nih.gov/pubmed/30886164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40596-5
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