Effects of (−)-Gallocatechin-3-Gallate on Tetrodotoxin-Resistant Voltage-Gated Sodium Channels in Rat Dorsal Root Ganglion Neurons

The (−)-gallocatechin-3-gallate (GCG) concentration in some tea beverages can account for as much as 50% of the total catechins. It has been shown that catechins have analgesic properties. Voltage-gated sodium channels (Nav) mediate neuronal action potentials. Tetrodotoxin inhibits all Nav isoforms,...

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Main Authors: Zhang, Yan, Jia, Yan-Yan, Guo, Jin-Lei, Liu, Pei-Qing, Jiang, Jian-Min
Format: Artigo
Language:Inglês
Published: Molecular Diversity Preservation International (MDPI) 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676812/
https://ncbi.nlm.nih.gov/pubmed/23652835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms14059779
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