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Modulation of Voltage-Gated Sodium Channel Activity in Human Dorsal Root Ganglion Neurons by Herpesvirus Quiescent Infection

The molecular mechanisms of pain associated with alphaherpesvirus latency are not clear. We hypothesize that the voltage-gated sodium channels (VGSC) on the dorsal root ganglion (DRG) neurons controlling electrical impulses may have abnormal activity during latent viral infection and reactivation. W...

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發表在:J Virol
Main Authors: Zhang, Qiaojuan, Martin-Caraballo, Miguel, Hsia, S. Victor
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000965/
https://ncbi.nlm.nih.gov/pubmed/31694955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01823-19
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