ATM mutations in hereditary pancreatic cancer patients

Genome-wide sequencing identified heterozygous, constitutional, Ataxia telangiectaisa mutated (ATM) gene mutations in two kindreds with familial pancreatic cancer. Mutations segregated with disease in both kindreds and tumor analysis demonstrated LOH of the wildtype allele. Sequence analysis of an a...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Roberts, Nicholas J., Jiao, Yuchen, Yu, Jun, Kopelovich, Levy, Petersen, Gloria M., Bondy, Melissa, Gallinger, Steven, Schwartz, Ann G., Syngal, Sapna, Cote, Michele L., Axilbund, Jennifer, Schulick, Richard, Ali, Syed Z., Eshleman, James R., Velculescu, Victor, Goggins, Michael, Vogelstein, Bert, Papadopoulous, Nikolas, Hruban, Ralph H., Kinzler, Kenneth W., Klein, Alison P.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2011
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676748/
https://ncbi.nlm.nih.gov/pubmed/22585167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-11-0194
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