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Intracellular Dialysis Disrupts Zn(2+) Dynamics and Enables Selective Detection of Zn(2+) Influx in Brain Slice Preparations

We examined the impact of intracellular dialysis on fluorescence detection of neuronal intracellular Zn(2+) accumulation. Comparison between two dialysis conditions (standard; 20minutes, brief; 2minutes) by standard whole-cell clamp revealed a high vulnerability of intracellular Zn(2+) buffers to in...

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Detalhes bibliográficos
Main Authors: Aiba, Isamu, West, Adrian K, Sheline, Christian T, Shuttleworth, C. William
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676454/
https://ncbi.nlm.nih.gov/pubmed/23517525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12246
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