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Carboxypeptidase E: a negative regulator of the canonical Wnt signaling pathway

Aberrant activation of the canonical Wnt signal transduction pathway is involved in many diseases including cancer and is especially implicated in the development and progression of colorectal cancer. The key effector protein of the canonical Wnt pathway is β-catenin, which functions with T-cell fac...

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Autori principali: Skalka, N, Caspi, M, Caspi, E, Loh, YP, Rosin-Arbesfeld, R
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676431/
https://ncbi.nlm.nih.gov/pubmed/22824791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.308
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