Accelerated Atherosclerosis in Apoe(−/−) Mice Heterozygous for the Insulin Receptor and the Insulin Receptor Substrate-1

OBJECTIVE: Prediabetic states are associated with accelerated atherosclerosis, but the availability of mouse models to study connections between these diseases has been limited. The aim of this study was to test the selective role of impaired insulin receptor/insulin receptor substrate-1 signaling o...

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Auteurs principaux: Galkina, Elena V., Butcher, Matthew, Keller, Susanna R., Goff, Matthew, Bruce, Anthony, Pei, Hong, Sarembock, Ian J., Sanders, John M., Nagelin, Melissa H., Srinivasan, Suseela, Kulkarni, Rohit N., Hedrick, Catherine C., Lattanzio, Frank A., Dobrian, Anca D., Nadler, Jerry L., Ley, Klaus
Format: Artigo
Langue:Inglês
Publié: 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676303/
https://ncbi.nlm.nih.gov/pubmed/22199371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.240358
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