Murine 12/15-Lipoxygenase Regulates ATP-binding Cassette Transporter G1 Protein Degradation through p38- and JNK2-dependent Pathways

12/15-Lipoxygenase (12/15LO) plays a role in the pathogenesis of atherosclerosis and diabetes and has been implicated in low density lipoprotein oxidation. Murine macrophages express high levels of 12/15LO and are key cells involved in the accumulation and efflux of oxidized low density lipoprotein...

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Bibliografiske detaljer
Main Authors: Nagelin, Melissa H., Srinivasan, Suseela, Nadler, Jerry L., Hedrick, Catherine C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781528/
https://ncbi.nlm.nih.gov/pubmed/19713213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.028910
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