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Blockade of IL-17A results in reduced atherosclerosis in Apoe-deficient mice

BACKGROUND: T cells play an important role during the immune response that accompanies atherosclerosis. To date, the role for IL-17A in atherogenesis is not well-defined. Here, we tested the hypothesis that atherosclerosis-prone conditions induce the differentiation of IL-17A-producing T cells, whic...

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Autors principals: Smith, Emily, Prasad, Konkal-Matt R., Butcher, Matthew, Dobrian, Anca, Kolls, Jay K, Ley, Klaus, Galkina, Elena
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929562/
https://ncbi.nlm.nih.gov/pubmed/20368519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.109.924886
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