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Accelerated Type 1 Diabetes Induction in Mice by Adoptive Transfer of Diabetogenic CD4+ T Cells

The nonobese diabetic (NOD) mouse spontaneously develops autoimmune diabetes after 12 weeks of age and is the most extensively studied animal model of human Type 1 diabetes (T1D). Cell transfer studies in irradiated recipient mice have established that T cells are pivotal in T1D pathogenesis in this...

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Bibliografski detalji
Glavni autori: Berry, Gregory, Waldner, Hanspeter
Format: Artigo
Jezik:Inglês
Izdano: MyJove Corporation 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676287/
https://ncbi.nlm.nih.gov/pubmed/23685789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/50389
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