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Genome-wide transcriptional analyses of islet-specific CD4+ T cells identify Idd9 genes controlling diabetogenic T cell function
Type 1 diabetes (T1D) is a polygenic disease with multiple insulin dependent diabetes loci (Idd) predisposing humans and non-obese diabetic (NOD) mice to disease. NOD.B10 Idd9 congenic mice, in which the NOD Idd9 chromosomal region is replaced by the Idd9 from T1D-resistant C57BL/10 mice, are signif...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4374160/ https://ncbi.nlm.nih.gov/pubmed/25672752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401288 |
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