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Primary DNA sequence determines sites of maintenance and de novo methylation by mammalian DNA methyltransferases.

Analysis of the enzymatic methylation of oligodeoxynucleotides containing multiple C-G groups showed that hemimethylated sites in duplex oligomers are not significantly methylated by human or murine DNA methyltransferase unless those sites are capable of being methylated de novo in the single- or do...

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Hlavní autoři: Bolden, A H, Nalin, C M, Ward, C A, Poonian, M S, Weissbach, A
Médium: Artigo
Jazyk:Inglês
Vydáno: 1986
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC367624/
https://ncbi.nlm.nih.gov/pubmed/3023872
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