Loading...
Neuromyelitis optica: Aquaporin-4 based pathogenesis mechanisms and new therapies
Neuromyelitis optica (NMO) is an autoimmune ‘aquaporinopathy’ of the central nervous system that causes inflammatory demyelinating lesions primarily in spinal cord and optic nerve, leading to paralysis and blindness. NMO lesions show loss of aquaporin-4 (AQP4), GFAP and myelin, infiltration of granu...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3676174/ https://ncbi.nlm.nih.gov/pubmed/22713791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2012.06.013 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|