In vivo localization of DNA topoisomerase II cleavage sites on Drosophila heat shock chromatin.
Similar to its inhibitory effect on mammalian DNA topoisomerase II, the cytotoxic drug VM26 (teniposide) also interferes with the breakage-reunion reaction of Drosophila melanogaster DNA topoisomerase II. VM26 induces topoisomerase II-mediated DNA breakage in vitro and in cultured D. melanogaster ce...
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| Udgivet i: | Mol Cell Biol |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
1986
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC367606/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3023886/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.6.4.985-992.1986 |
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