The recognition of DNA cleavage sites by porcine spleen topoisomerase II.
The cutting sites specificity of topoisomerase II from porcine spleen were determined by a modified Sanger's DNA sequencing method. The topoisomerase II prefers to cut DNA at the 3' side of A and leave 5' protruding end with two staggering bases. Through the free energy analysis for DNA duplex, we a...
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| Udgivet i: | Nucleic Acids Res |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1992
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| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310409/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1311075/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.3.467 |
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