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Drosophila topoisomerase II double-strand DNA cleavage: analysis of DNA sequence homology at the cleavage site.

In order to study the sequence specificity of double-strand DNA cleavage by Drosophila topoisomerase II, we have mapped and sequenced 16 strong and 47 weak cleavage sites in the recombinant plasmid p pi 25.1. Analysis of the nucleotide and dinucleotide frequencies in the region near the site of phos...

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Autors principals: Sander, M, Hsieh, T S
Format: Artigo
Idioma:Inglês
Publicat: 1985
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC341056/
https://ncbi.nlm.nih.gov/pubmed/2987816
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