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Integration of simian virus 40 into cellular DNA occurs at or near topoisomerase II cleavage hot spots induced by VM-26 (teniposide).

Inhibition of DNA topoisomerase II in simian virus 40 (SV40)-infected BSC-1 cells with a topoisomerase II poison, VM-26 (teniposide), resulted in rapid conversion of a population of the SV40 DNA into a high-molecular-weight form. Characterization of this high-molecular-weight form of SV40 DNA sugges...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Biol
Autori principali: Bodley, A L, Huang, H C, Yu, C, Liu, L F
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 1993
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364678/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8413219/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.10.6190-6200.1993
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