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In vivo localization of DNA topoisomerase II cleavage sites on Drosophila heat shock chromatin.

Similar to its inhibitory effect on mammalian DNA topoisomerase II, the cytotoxic drug VM26 (teniposide) also interferes with the breakage-reunion reaction of Drosophila melanogaster DNA topoisomerase II. VM26 induces topoisomerase II-mediated DNA breakage in vitro and in cultured D. melanogaster ce...

詳細記述

保存先:
書誌詳細
主要な著者: Rowe, T C, Wang, J C, Liu, L F
フォーマット: Artigo
言語:Inglês
出版事項: 1986
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC367606/
https://ncbi.nlm.nih.gov/pubmed/3023886
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