Toll-Like Receptor 4/Stem Cell Antigen 1 Signaling Promotes Hematopoietic Precursor Cell Commitment to Granulocyte Development during the Granulopoietic Response to Escherichia coli Bacteremia

In response to severe bacterial infection, bone marrow hematopoietic activity shifts toward promoting granulopoiesis. The underlying cell signaling mechanisms remain obscure. To study the role of Toll-like receptor 4 (TLR4)/stem cell antigen-1 (Sca-1) signaling in this process, bacteremia was induce...

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Hlavní autoři: Shi, Xin, Siggins, Robert W., Stanford, William L., Melvan, John N., Basson, Marc D., Zhang, Ping
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
Host Response and Inflammation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676006/
https://ncbi.nlm.nih.gov/pubmed/23545304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01280-12
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