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Toll-Like Receptor 4/Stem Cell Antigen 1 Signaling Promotes Hematopoietic Precursor Cell Commitment to Granulocyte Development during the Granulopoietic Response to Escherichia coli Bacteremia

In response to severe bacterial infection, bone marrow hematopoietic activity shifts toward promoting granulopoiesis. The underlying cell signaling mechanisms remain obscure. To study the role of Toll-like receptor 4 (TLR4)/stem cell antigen-1 (Sca-1) signaling in this process, bacteremia was induce...

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書誌詳細
主要な著者: Shi, Xin, Siggins, Robert W., Stanford, William L., Melvan, John N., Basson, Marc D., Zhang, Ping
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676006/
https://ncbi.nlm.nih.gov/pubmed/23545304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01280-12
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