Cubilin, a High Affinity Receptor for Fibroblast Growth Factor 8, Is Required for Cell Survival in the Developing Vertebrate Head

Cubilin (Cubn) is a multiligand endocytic receptor critical for the intestinal absorption of vitamin B12 and renal protein reabsorption. During mouse development, Cubn is expressed in both embryonic and extra-embryonic tissues, and Cubn gene inactivation results in early embryo lethality most likely...

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Detalhes bibliográficos
Main Authors: Cases, Olivier, Perea-Gomez, Aitana, Aguiar, Diego P., Nykjaer, Anders, Amsellem, Sabine, Chandellier, Jacqueline, Umbhauer, Muriel, Cereghini, Silvia, Madsen, Mette, Collignon, Jérôme, Verroust, Pierre, Riou, Jean-François, Creuzet, Sophie E., Kozyraki, Renata
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675600/
https://ncbi.nlm.nih.gov/pubmed/23592779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.451070
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