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Loss of Cubilin, the intrinsic factor-vitamin B12 receptor, impairs visceral endoderm endocytosis and endodermal patterning in the mouse

The visceral endoderm is a polarized epithelial monolayer necessary for early embryonic development in rodents. A key feature of this epithelium is an active endocytosis and degradation of maternal nutrients, in addition to being the source of various signaling molecules or inhibitors required for t...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Perea-Gomez, Aitana, Cases, Olivier, Lelièvre, Vincent, Pulina, Maria V., Collignon, Jérôme, Hadjantonakis, Anna-Katerina, Kozyraki, Renata
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629654/
https://ncbi.nlm.nih.gov/pubmed/31308417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46559-0
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