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Exploring mRNA 3′-UTR G-quadruplexes: evidence of roles in both alternative polyadenylation and mRNA shortening

Guanine-rich RNA sequences can fold into non-canonical, four stranded helical structures called G-quadruplexes that have been shown to be widely distributed within the mammalian transcriptome, as well as being key regulatory elements in various biological mechanisms. That said, their role within the...

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Bibliografske podrobnosti
Main Authors: Beaudoin, Jean-Denis, Perreault, Jean-Pierre
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2013
Teme:
RNA
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675481/
https://ncbi.nlm.nih.gov/pubmed/23609544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt265
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