Hypermethylation of the CpG Island Near the G(4)C(2) Repeat in ALS with a C9orf72 Expansion

The G(4)C(2) repeat expansion in C9orf72 is the most common known cause of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). We tested the hypothesis that the repeat expansion causes aberrant CpG methylation near the G(4)C(2) repeat, which could be responsible for the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Xi, Zhengrui, Zinman, Lorne, Moreno, Danielle, Schymick, Jennifer, Liang, Yan, Sato, Christine, Zheng, Yonglan, Ghani, Mahdi, Dib, Samar, Keith, Julia, Robertson, Janice, Rogaeva, Ekaterina
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2013
Pynciau:
Report
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675239/
https://ncbi.nlm.nih.gov/pubmed/23731538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2013.04.017
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