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Hypermethylation of the CpG Island Near the G(4)C(2) Repeat in ALS with a C9orf72 Expansion
The G(4)C(2) repeat expansion in C9orf72 is the most common known cause of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). We tested the hypothesis that the repeat expansion causes aberrant CpG methylation near the G(4)C(2) repeat, which could be responsible for the...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Elsevier
2013
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3675239/ https://ncbi.nlm.nih.gov/pubmed/23731538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2013.04.017 |
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