A Genome-Wide Screen of CREB Occupancy Identifies the RhoA Inhibitors Par6C and Rnd3 as Regulators of BDNF-Induced Synaptogenesis

Neurotrophin-regulated gene expression is believed to play a key role in long-term changes in synaptic structure and the formation of dendritic spines. Brain-derived neurotrophic factor (BDNF) has been shown to induce increases in dendritic spine formation, and this process is thought to function in...

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Hlavní autoři: Lesiak, Adam, Pelz, Carl, Ando, Hideaki, Zhu, Mingyan, Davare, Monika, Lambert, Talley J., Hansen, Katelin F., Obrietan, Karl, Appleyard, Suzanne M., Impey, Soren, Wayman, Gary A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675129/
https://ncbi.nlm.nih.gov/pubmed/23762244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064658
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