Nalaganje...
Structural Basis and Selectivity of Tankyrase Inhibition by a Wnt Signaling Inhibitor WIKI4
Recently a novel inhibitor of Wnt signaling was discovered. The compound, WIKI4, was found to act through tankyrase inhibition and regulate β-catenin levels in many cancer cell lines and human embryonic stem cells. Here we confirm that WIKI4 is a high potency tankyrase inhibitor and that it selectiv...
Shranjeno v:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2013
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3675114/ https://ncbi.nlm.nih.gov/pubmed/23762361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065404 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|