Interaction between NBS1 and the mTOR/Rictor/SIN1 Complex through Specific Domains

Nijmegen breakage syndrome (NBS) is a chromosomal-instability syndrome. The NBS gene product, NBS1 (p95 or nibrin), is a part of the Mre11-Rad50-NBS1 complex. SIN1 is a component of the mTOR/Rictor/SIN1 complex mediating the activation of Akt. Here we show that NBS1 interacted with mTOR, Rictor, and...

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Detalhes bibliográficos
Main Authors: Wang, Jian-Qiu, Chen, Jian-Hong, Chen, Yen-Chung, Chen, Mei-Yu, Hsieh, Chia-Ying, Teng, Shu-Chun, Wu, Kou-Juey
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675082/
https://ncbi.nlm.nih.gov/pubmed/23762398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065586
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