Dengue Virus Activates Membrane TRAIL Relocalization and IFN-α Production by Human Plasmacytoid Dendritic Cells In Vitro and In Vivo

BACKGROUND: Dengue displays a broad spectrum of clinical manifestations that may vary from asymptomatic to severe and even fatal features. Plasma leakage/hemorrhages can be caused by a cytokine storm induced by monocytes and dendritic cells during dengue virus (DENV) replication. Plasmacytoid dendri...

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Main Authors: Gandini, Mariana, Gras, Christophe, Azeredo, Elzinandes Leal, Pinto, Luzia Maria de Oliveira, Smith, Nikaïa, Despres, Philippe, da Cunha, Rivaldo Venâncio, de Souza, Luiz José, Kubelka, Claire Fernandes, Herbeuval, Jean-Philippe
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675005/
https://ncbi.nlm.nih.gov/pubmed/23755314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002257
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