HMGB1 Is Involved in IFN-α Production and TRAIL Expression by HIV-1-Exposed Plasmacytoid Dendritic Cells: Impact of the Crosstalk with NK Cells

Plasmacytoid dendritic cells (pDCs) are innate sensors of viral infections and important mediators of antiviral innate immunity through their ability to produce large amounts of IFN-α. Moreover, Toll-like receptor 7 (TLR7) and 9 (TLR9) ligands, such as HIV and CpG respectively, turn pDCs into TRAIL-...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Saïdi, Héla, Bras, Marlène, Formaglio, Pauline, Melki, Marie-Thérèse, Charbit, Bruno, Herbeuval, Jean-Philippe, Gougeon, Marie-Lise
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752468/
https://ncbi.nlm.nih.gov/pubmed/26871575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005407
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