HMGB1 Is Involved in IFN-α Production and TRAIL Expression by HIV-1-Exposed Plasmacytoid Dendritic Cells: Impact of the Crosstalk with NK Cells

Plasmacytoid dendritic cells (pDCs) are innate sensors of viral infections and important mediators of antiviral innate immunity through their ability to produce large amounts of IFN-α. Moreover, Toll-like receptor 7 (TLR7) and 9 (TLR9) ligands, such as HIV and CpG respectively, turn pDCs into TRAIL-...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS Pathog
Päätekijät: Saïdi, Héla, Bras, Marlène, Formaglio, Pauline, Melki, Marie-Thérèse, Charbit, Bruno, Herbeuval, Jean-Philippe, Gougeon, Marie-Lise
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2016
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752468/
https://ncbi.nlm.nih.gov/pubmed/26871575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005407
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