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Functional divergence of the brain-size regulating gene MCPH1 during primate evolution and the origin of humans

BACKGROUND: One of the key genes that regulate human brain size, MCPH1 has evolved under strong Darwinian positive selection during the evolution of primates. During this evolution, the divergence of MCPH1 protein sequences among primates may have caused functional changes that contribute to brain e...

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Autori principali: Shi, Lei, Li, Ming, Lin, Qiang, Qi, Xuebin, Su, Bing
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674976/
https://ncbi.nlm.nih.gov/pubmed/23697381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-11-62
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