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Functional divergence of the brain-size regulating gene MCPH1 during primate evolution and the origin of humans
BACKGROUND: One of the key genes that regulate human brain size, MCPH1 has evolved under strong Darwinian positive selection during the evolution of primates. During this evolution, the divergence of MCPH1 protein sequences among primates may have caused functional changes that contribute to brain e...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3674976/ https://ncbi.nlm.nih.gov/pubmed/23697381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-11-62 |
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