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Single-molecule photobleaching reveals increased MET receptor dimerization upon ligand binding in intact cells

BACKGROUND: The human receptor tyrosine kinase MET and its ligand hepatocyte growth factor/scatter factor are essential during embryonic development and play an important role during cancer metastasis and tissue regeneration. In addition, it was found that MET is also relevant for infectious disease...

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Detalhes bibliográficos
Main Authors: Dietz, Marina S, Haße, Daniel, Ferraris, Davide M, Göhler, Antonia, Niemann, Hartmut H, Heilemann, Mike
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674922/
https://ncbi.nlm.nih.gov/pubmed/23731667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2046-1682-6-6
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