BMP antagonists enhance myogenic differentiation and ameliorate the dystrophic phenotype in a DMD mouse model

Duchenne Muscular Dystrophy (DMD) is an X-linked lethal muscle wasting disease characterized by muscle fiber degeneration and necrosis. The progressive pathology of DMD can be explained by an insufficient regenerative response resulting in fibrosis and adipose tissue formation. BMPs are known to inh...

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Autores principales: Shi, SongTing, Hoogaars, Willem M.H., de Gorter, David J.J., van Heiningen, Sandra H., Lin, Herbert Y., Hong, Charles C., Kemaladewi, Dwi U., Aartsma-Rus, Annemieke, Dijke, Peter ten, ’t Hoen, Peter A.C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674857/
https://ncbi.nlm.nih.gov/pubmed/20940052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2010.10.003
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