BMP antagonists enhance myogenic differentiation and ameliorate the dystrophic phenotype in a DMD mouse model

Duchenne Muscular Dystrophy (DMD) is an X-linked lethal muscle wasting disease characterized by muscle fiber degeneration and necrosis. The progressive pathology of DMD can be explained by an insufficient regenerative response resulting in fibrosis and adipose tissue formation. BMPs are known to inh...

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Main Authors: Shi, SongTing, Hoogaars, Willem M.H., de Gorter, David J.J., van Heiningen, Sandra H., Lin, Herbert Y., Hong, Charles C., Kemaladewi, Dwi U., Aartsma-Rus, Annemieke, Dijke, Peter ten, ’t Hoen, Peter A.C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674857/
https://ncbi.nlm.nih.gov/pubmed/20940052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2010.10.003
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