Restricting HIV-1 pathways for escape using rationally designed anti–HIV-1 antibodies

Recently identified broadly neutralizing antibodies (bNAbs) that potently neutralize most HIV-1 strains are key to potential antibody-based therapeutic approaches to combat HIV/AIDS in the absence of an effective vaccine. Increasing bNAb potencies and resistance to common routes of HIV-1 escape thro...

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Detalhes bibliográficos
Main Authors: Diskin, Ron, Klein, Florian, Horwitz, Joshua A., Halper-Stromberg, Ariel, Sather, D. Noah, Marcovecchio, Paola M., Lee, Terri, West, Anthony P., Gao, Han, Seaman, Michael S., Stamatatos, Leonidas, Nussenzweig, Michel C., Bjorkman, Pamela J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674693/
https://ncbi.nlm.nih.gov/pubmed/23712429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20130221
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