Citrullinated fibronectin inhibits apoptosis and promotes the secretion of pro-inflammatory cytokines in fibroblast-like synoviocytes in rheumatoid arthritis

INTRODUCTION: Rheumatoid arthritis (RA) is characterized by synovial lining hyperplasia, in which there may be an imbalance between the growth and death of fibroblast-like synoviocytes (FLSs). Antibodies against citrullinated proteins are proposed to induce RA. This study aimed to investigate the pa...

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Hauptverfasser: Fan, Lieying, Wang, Qiang, Liu, Rongqing, Zong, Ming, He, Dongyi, Zhang, Hui, Ding, Yuanyuan, Ma, Jianwei
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674622/
https://ncbi.nlm.nih.gov/pubmed/23217276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4112
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