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Excessive bone formation in a mouse model of ankylosing spondylitis is associated with decreases in Wnt pathway inhibitors

INTRODUCTION: Ankylosing spondylitis (AS) is unique in its pathology where inflammation commences at the entheses before progressing to an osteoproliferative phenotype generating excessive bone formation that can result in joint fusion. The underlying mechanisms of this progression are poorly unders...

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Detalhes bibliográficos
Main Authors: Haynes, Katelin R, Pettit, Allison R, Duan, Ran, Tseng, Hsu-Wen, Glant, Tibor T, Brown, Matthew A, Thomas, Gethin P
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674607/
https://ncbi.nlm.nih.gov/pubmed/23171658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4096
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