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Sirtuin deacetylases in neurodegenerative diseases of aging
Sirtuin enzymes are a family of highly conserved protein deacetylases that depend on nicotinamide adenine dinucleotide (NAD+) for their activity. There are seven sirtuins in mammals and these proteins have been linked with caloric restriction and aging by modulating energy metabolism, genomic stabil...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3674397/ https://ncbi.nlm.nih.gov/pubmed/23689277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.70 |
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