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Sirtuin deacetylases in neurodegenerative diseases of aging

Sirtuin enzymes are a family of highly conserved protein deacetylases that depend on nicotinamide adenine dinucleotide (NAD+) for their activity. There are seven sirtuins in mammals and these proteins have been linked with caloric restriction and aging by modulating energy metabolism, genomic stabil...

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Bibliografische gegevens
Hoofdauteurs: Herskovits, Adrianna Z, Guarente, Leonard
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674397/
https://ncbi.nlm.nih.gov/pubmed/23689277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.70
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