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Sirtuin deacetylases in neurodegenerative diseases of aging

Sirtuin enzymes are a family of highly conserved protein deacetylases that depend on nicotinamide adenine dinucleotide (NAD+) for their activity. There are seven sirtuins in mammals and these proteins have been linked with caloric restriction and aging by modulating energy metabolism, genomic stabil...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Herskovits, Adrianna Z, Guarente, Leonard
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674397/
https://ncbi.nlm.nih.gov/pubmed/23689277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.70
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