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A critical role of toll-like receptor 4 (TLR4) and its' in vivo ligands in basal radio-resistance

Toll-like receptor-4 (TLR4) plays a critical role in innate and acquired immunity, but its role in radio-resistance is unknown. We used TLR4 knockout (KO,(−/−)) mice and gut commensal depletion methods, to test the influence of TLR4 and its' in vivo agonist on basal radio-resistance. We found t...

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Hlavní autoři: Liu, C, Zhang, C, Mitchel, R EJ, Cui, J, Lin, J, Yang, Y, Liu, X, Cai, J
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674368/
https://ncbi.nlm.nih.gov/pubmed/23722538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.161
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