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In vivo priming of IL-17(+) uveitogenic T cells is enhanced by Toll ligand receptor (TLR)2 and TLR4 agonists via γδ T cell activation

We investigated the in vivo priming of IL-17(+) autoreactive T cells in experimental autoimmune uveitis-prone C57BL/6 (B6) and B10RIII mice using a combination of approaches, including limiting dilution assay. High numbers of in vivo primed IL-17(+) interphotoreceptor retinoid-binding protein (IRBP)...

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Main Authors: Zuo, Aijun, Liang, Dongchun, Shao, Hui, Born, Willi K., Kaplan, Henry J., Sun, Deming
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288362/
https://ncbi.nlm.nih.gov/pubmed/22301006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2011.12.013
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