IP(3)R2 levels dictate the apoptotic sensitivity of diffuse large B-cell lymphoma cells to an IP(3)R-derived peptide targeting the BH4 domain of Bcl-2

Disrupting inositol 1,4,5-trisphosphate (IP(3)) receptor (IP(3)R)/B-cell lymphoma 2 (Bcl-2) complexes using a cell-permeable peptide (stabilized TAT-fused IP(3)R-derived peptide (TAT-IDP(S))) that selectively targets the BH4 domain of Bcl-2 but not that of B-cell lymphoma 2-extra large (Bcl-Xl) pote...

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Detalhes bibliográficos
Main Authors: Akl, H, Monaco, G, La Rovere, R, Welkenhuyzen, K, Kiviluoto, S, Vervliet, T, Molgó, J, Distelhorst, C W, Missiaen, L, Mikoshiba, K, Parys, J B, De Smedt, H, Bultynck, G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674349/
https://ncbi.nlm.nih.gov/pubmed/23681227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.140
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